BACKGROUND AND AIM: Pneumonia is among the leading causes of morbidity and mortality worldwide. This study aims to investigate the impact of the Glasgow Prognostic Score (GPS) on the prognosis of patients hospitalized with community-acquired pneumonia (CAP).

METHODS: Patients hospitalized in our department due to CAP were retrospectively reviewed. The GPS was calculated using C-reactive protein (CRP) and albumin levels.

RESULTS: The study was conducted with a total of 121 patients, 80 (66.1%) of whom were male. The median age was 70 years. Early mortality was observed in 11 (9.1%) patients. The length of hospital stay for patients with a GPS of 2 was statistically significantly longer than for those with a GPS ≤1 (p=0.002). Similarly, early mortality rates for patients with a GPS of 2 (17.3%) were statistically significantly higher than for those with a GPS ≤1 (2.9%) (p=0.009). A ROC curve analysis was performed to determine the cutoff point for predicting mortality using the GPS. It was found that GPS values of 1.5 or higher could predict mortality with a sensitivity of 81.82% and a specificity of 60.91%. Age, average length of hospital stay, and incidence of malignancy were statistically significant and higher in patients who died within 30 days compared to those who survived.(p=0.011, p=0.001, and p=0.041, respectively). Upon evaluating the effects of age, length of hospital stay, GPS, and malignancy, which were found to be significant in univariate analyses, through logistic regression analysis, GPS was not found to have a significant impact on mortality.

CONCLUSION: The GPS is associated with early mortality in CAP. However, its independent impact on mortality is not statistically significant when other factors such as age, length of hospital stay, and malignancy are considered. This suggests that while GPS can be a useful indicator in the initial assessment, its prognostic value may be limited when other clinical variables are taken into account.